Adipose tissue (fat) is an active endocrine organ that plays a
central role in the modulation of metabolic homeostasis, inflammation, and
energy balance. Dysregulation of fat accumulation contributes to a wide range
of health problems such as obesity and metabolic syndrome, diabetes and
cardiovascular diseases.
CAL010 is a first-in-class fat reduction agent that selectively kills adipocytes and dose-dependently reduces target adipose tissue mass without inflammatory side effects. CAL010 is also being developed for systemic reduction adipose mass with preservation of muscle mass.
